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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  40nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  130nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  150nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  180nMAssay Description:In vitro inhibitory activity against the ectodomain of the human matrix metalloproteinase-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  200nMAssay Description:Inhibition of matrix metalloproteinase-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  339nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  340nMAssay Description:In Vitro inhibitory activity against the catalytic domain of the matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
UniversitäT Bielefeld

Curated by ChEMBL
LigandPNGBDBM50104718((R)-N-(5-(4-bromophenyl)-6H-1,3,4-thiadiazin-2-yl)...)
Affinity DataKi:  420nMAssay Description:In vitro inhibitory activity against the catalytic domain of the human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed