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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: 5.40E+3nM
Assay Description:
Inhibition of human recombinant MK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Aurora kinase B
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: 1.08E+4nM
Assay Description:
Inhibition of Aurora B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Casein kinase I isoform gamma-1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: 1.16E+4nM
Assay Description:
Inhibition of CK1-gamma1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: 1.53E+4nM
Assay Description:
Inhibition of FYN (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: 3.62E+4nM
Assay Description:
Inhibition of PDGFRalpha (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of p38alpha (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of ERK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of RSK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of ROCK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Protein kinase C alpha type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of PKCalpha (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit alpha
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of IKKalpha (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50259638
(3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-ph...)
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Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of SRC (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI