Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428716(CHEMBL2333128 | US9884828, 2-41)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428716(CHEMBL2333128 | US9884828, 2-41)
Affinity DataIC50: <6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428716(CHEMBL2333128 | US9884828, 2-41)
Affinity DataIC50:  17nMAssay Description:Inhibition of CSF1R (unknown origin) by TR-FRET assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50428716(CHEMBL2333128 | US9884828, 2-41)
Affinity DataIC50:  54nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by TR-FRET assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed