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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173834
((R)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase kinase kinase 8
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173834
((R)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of human Tpl2 by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI