Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30nM
Assay Description:
Displacement of [3H]DAMGO from MOR in rat brain membrane measured after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 258nM
Assay Description:
Displacement of [3H]DSLET from DOR in rat brain membrane measured after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Clinical Research Institute Of Montreal
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.49E+4nM
Assay Description:
Displacement of [3H]U69,593 from KOR in guinea pig brain membrane measured after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
Assay Description:
Compound was evaluated for the inhibition of binding of [3H]naloxone toOpioid receptor mu 1 of rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
National University Of Singapore
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
Assay Description:
Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced response
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Rattus norvegicus (rat))
Clinical Research Institute Of Montreal
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.35E+4nM
Assay Description:
Inhibition of [3H]-DPDPE binding to Opioid receptor delta 1 of rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
National University Of Singapore
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.35E+4nM
Assay Description:
Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced response
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50252861
(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 100nM
Assay Description:
Effective concentration required for maximum agonist response at melanocortin 1 receptor from frog skin.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI