Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50337103(2'-((1R)-1-{(2R)-3-[1-(4-Chloro-3-fluorophenyl)-2-...)Copy SMILESCopy InChI

Affinity DataIC50:  12nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12h cells by reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50337103(2'-((1R)-1-{(2R)-3-[1-(4-Chloro-3-fluorophenyl)-2-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of beta2 adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50337103(2'-((1R)-1-{(2R)-3-[1-(4-Chloro-3-fluorophenyl)-2-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI