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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Evotec International
US Patent
Ligand
BDBM181439
(US9139577, 2.048 | US9708274, 2.048)
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Affinity Data
IC50: 2nM
T: 2°C
Assay Description:
The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Evotec International
US Patent
Ligand
BDBM181439
(US9139577, 2.048 | US9708274, 2.048)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Evotec International
US Patent
Ligand
BDBM181439
(US9139577, 2.048 | US9708274, 2.048)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
pH: 7.5
Assay Description:
The inhibition of kinase activity of MNK1a was assessed using pre-activated GST-MNK1a. The 2xMKNK1 (MNK1) mixture is prepared in 50 mM HEPES pH 7.5, ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Evotec International
US Patent
Ligand
BDBM181439
(US9139577, 2.048 | US9708274, 2.048)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
The Z-LYTE biochemical assay employs a fluorescence-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated and n...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI