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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Tyrosine-protein kinase SYK [342-635]
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM311122
(US10155751, Example 9)
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Affinity Data
IC50: 1.10nM
Assay Description:
Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Receptor-type tyrosine-protein kinase FLT3 [564-960]
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM311122
(US10155751, Example 9)
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Affinity Data
IC50: 1.84E+3nM
Assay Description:
Recombinant human FLT3 (amino acids 564-958, Molecular weight 48.6 kDa, Invitrogen #PR4666C) was expressed with an Histidine tag. The test compounds...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Aurora kinase B [1-341]
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM311122
(US10155751, Example 9)
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Affinity Data
IC50: 2.33E+4nM
Assay Description:
Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI