Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50341791
((1S,2R,3R)-1-[(R)-4-(4-Fluorophenyl)-3-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50341791
((1S,2R,3R)-1-[(R)-4-(4-Fluorophenyl)-3-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant TACE after 60 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50341791
((1S,2R,3R)-1-[(R)-4-(4-Fluorophenyl)-3-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50341791
((1S,2R,3R)-1-[(R)-4-(4-Fluorophenyl)-3-methylpiper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI