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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341820((1S,2R,3R)-1-(6-Fluoro-4H-thieno[3,2-b]indole-2-su...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341820((1S,2R,3R)-1-(6-Fluoro-4H-thieno[3,2-b]indole-2-su...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341820((1S,2R,3R)-1-(6-Fluoro-4H-thieno[3,2-b]indole-2-su...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341820((1S,2R,3R)-1-(6-Fluoro-4H-thieno[3,2-b]indole-2-su...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed