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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50418257
(CHEMBL1765730)
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Affinity Data
IC50: 126nM
Assay Description:
Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50418257
(CHEMBL1765730)
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Copy InChI
Affinity Data
IC50: 7.94E+3nM
Assay Description:
Inhibition of ALK5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50418257
(CHEMBL1765730)
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Copy InChI
Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of aurora A
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50418257
(CHEMBL1765730)
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Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of ROCK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50418257
(CHEMBL1765730)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.51E+4nM
Assay Description:
Inhibition of aurora B
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI