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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50252244
((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50252244
((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50252244
((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Rattus norvegicus (rat))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50252244
((2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 42nM
Assay Description:
Inhibition of rat 11betaHSD1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI