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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297144
((R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahyd...)
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Affinity Data
IC50: 52nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297144
((R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.32E+3nM
Assay Description:
Inhibition of MK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50297144
((R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70E+4nM
Assay Description:
Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI