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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Metabotropic glutamate receptor 1
(RAT)
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50224409
(9-(4-chlorophenyl)-2,3-dihydro-2(R)-methyl-1H-pyri...)
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Affinity Data
Ki: 9.10nM
Assay Description:
Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50224409
(9-(4-chlorophenyl)-2,3-dihydro-2(R)-methyl-1H-pyri...)
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Affinity Data
IC50: 24nM
Assay Description:
Antagonist activity at human mGluR1a expressed in CHO cells assessed by measuring intracellular calcium by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50224409
(9-(4-chlorophenyl)-2,3-dihydro-2(R)-methyl-1H-pyri...)
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Affinity Data
IC50: >1.00E+3nM
Assay Description:
Antagonist activity at human mGluR5b expressed in HEK293 cells assessed by measuring intracellular calcium by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI