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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi:  167nMAssay Description:Displacement of [3H]diprenorphine from rat KOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi:  299nMAssay Description:Displacement of [3H]DAMGO from rat MOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]DPDPE from mouse DOP stably expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50:  397nMAssay Description:Antagonist activity at human KOP stably expressed in CHO cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50268529((3S,6R,9S,14aR)-6-((1H-indol-3-yl)methyl)-9-benzyl...)
Affinity DataIC50:  1.47E+3nMAssay Description:Antagonist activity at human MOP stably expressed in CHO cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails PubMed