Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMuscarinic acetylcholine receptor M2(RAT)
TBA

Curated by ChEMBL

LigandBDBM50284323(2,2-Dimethyl-propionic acid (1R,3S,3aR,4R,4aS,8aR,...)Copy SMILESCopy InChI

Affinity DataKd:  464nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50284323(2,2-Dimethyl-propionic acid (1R,3S,3aR,4R,4aS,8aR,...)Copy SMILESCopy InChI

Affinity DataKd:  2.52E+3nMAssay Description:Binding affinity against M1 receptor expressed in CHO-K1 cells transfected with human muscarinic receptor sequence using radioligand [3H]-quinuclidin...More data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI