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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
N-acylethanolamine-hydrolyzing acid amidase
(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50439661
(CHEMBL2419822 | US9353075, 5)
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Affinity Data
IC50: 389nM
Assay Description:
Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
N-acylethanolamine-hydrolyzing acid amidase
(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50439661
(CHEMBL2419822 | US9353075, 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 390nM
Assay Description:
Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
N-acylethanolamine-hydrolyzing acid amidase
(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50439661
(CHEMBL2419822 | US9353075, 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 390nM
Assay Description:
Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
N-acylethanolamine-hydrolyzing acid amidase
(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by
ChEMBL
Ligand
BDBM50439661
(CHEMBL2419822 | US9353075, 5)
Copy SMILES
Copy InChI
Affinity Data
IC50: 390nM
pH: 7.4
Assay Description:
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI