Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50439661(CHEMBL2419822 | US9353075, 5)
Affinity DataIC50:  389nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50439661(CHEMBL2419822 | US9353075, 5)
Affinity DataIC50:  390nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50439661(CHEMBL2419822 | US9353075, 5)
Affinity DataIC50:  390nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50439661(CHEMBL2419822 | US9353075, 5)
Affinity DataIC50:  390nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
In DepthDetails US Patent