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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Muscarinic acetylcholine receptor M1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50005848
((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
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Affinity Data
Ki: 90nM
Assay Description:
In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50005848
((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.58E+3nM
Assay Description:
In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM50005848
((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30E+3nM
Assay Description:
Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM50005848
((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
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Copy InChI
Affinity Data
Ki: >2.10E+4nM
Assay Description:
Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor
(Cavia porcellus)
Uppsala University
Curated by
ChEMBL
Ligand
BDBM50005848
((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,4...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.50E+4nM
Assay Description:
Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI