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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
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Affinity Data
Ki: 0.640nM
Assay Description:
Displacement of [3H]methyltrienolone from human mineralocorticoid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.56nM
Assay Description:
Binding affinity to human mineralocorticoid receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.39nM
Assay Description:
Displacement of [3H]methyltrienolone from human glucocorticoid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 137nM
Assay Description:
Binding affinity to human progesterone receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 167nM
Assay Description:
Binding affinity to human glucocorticoid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 220nM
Assay Description:
Displacement of [3H]methyltrienolone from human androgen receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 454nM
Assay Description:
Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 849nM
Assay Description:
Binding affinity to human androgen receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Estrogen receptor
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.10E+3nM
Assay Description:
Binding affinity to human estrogen receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64.1nM
Assay Description:
Antagonist activity at human mineralocorticoid receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50228079
((R)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 765nM
Assay Description:
Antagonist activity at human progesterone receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by GRE-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI