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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50334686
(CHEMBL1642590 | N-((4S)-4-(cyanomethyl)-4-phenylcy...)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of human full length 11beta-HSD1 assessed as inhibition of conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50334686
(CHEMBL1642590 | N-((4S)-4-(cyanomethyl)-4-phenylcy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of human recombinant full length 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of conversion of [3H]cortisone to [3H]cortis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI