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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50248101
(CHEMBL460923 | N-((1S,4R)-4-cyano-4-(4-cyanophenyl...)
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Affinity Data
IC50: 43nM
Assay Description:
Inhibition of FLAG-tagged full length human 11beta-HSD1 expressed in baculovirus-infected Trichoplusia ni Hi5 cells assessed as reduction of [3H]cort...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50248101
(CHEMBL460923 | N-((1S,4R)-4-cyano-4-(4-cyanophenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 82nM
Assay Description:
Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPH
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50248101
(CHEMBL460923 | N-((1S,4R)-4-cyano-4-(4-cyanophenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >300nM
Assay Description:
Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albumin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI