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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50243632
((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
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Affinity Data
IC50: 0.800nM
Assay Description:
Inhibition of human cloned 11beta-HSD1 by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50243632
((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40nM
Assay Description:
Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50243632
((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 38nM
Assay Description:
Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albumin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase type 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50243632
((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 11beta-HSD2 by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI