Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen

US Patent

LigandBDBM215353(US9296736, 321 | US9593129, Example 321)Copy SMILESCopy InChI

Affinity DataIC50:  1.30nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen

US Patent

LigandBDBM215353(US9296736, 321 | US9593129, Example 321)Copy SMILESCopy InChI

Affinity DataIC50:  1.30nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI