Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAromatase(Homo sapiens (Human))
Tohoku Pharmaceutical University

LigandBDBM9987((2R,6S,15S)-6-hydroxy-2,15-dimethyltetracyclo[8.7....)Copy SMILESCopy InChI

Affinity DataKi:  25nM ΔG°:  -45.1kJ/mole IC50:  280nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetAromatase(Homo sapiens (Human))
Tohoku Pharmaceutical University

LigandBDBM50135790(CHEMBL3349864)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomes after 5 mins by Dixon plot analysis in presence of [1beta-3H]ADMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI