Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAromatase(Homo sapiens (Human))
Tohoku Pharmaceutical University

LigandBDBM9985((2S,6R,15S)-6-hydroxy-2-(hydroxymethyl)-15-methylt...)Copy SMILESCopy InChI

Affinity DataKi:  800nM ΔG°:  -36.2kJ/mole IC50:  6.80E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

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TargetAromatase(Homo sapiens (Human))
Tohoku Pharmaceutical University

LigandBDBM50332823((4R,8R,9S,10S,13S,14S)-4-hydroxy-10-(hydroxymethyl...)Copy SMILESCopy InChI

Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human placental aromataseChecked by AuthorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI