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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Di Perugia

LigandPNGBDBM21678((2S,4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-5,9...)
Affinity DataEC50:  140nMpH: 7.2 T: 2°CAssay Description:For transient transfection assays to analyze TGR5 activity, Chinese hamster ovary (CHO) cells were transfected with hTGR5 expression plasmid, cAMP-re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50151413((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-6,10,13-tr...)
Affinity DataEC50:  1.56E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21678((2S,4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-5,9...)
Affinity DataEC50:  1.16E+4nMpH: 7.2 T: 2°CAssay Description:To evaluate FXR activity of compounds, COS1 (ATCC) cells were transfected with hFXR expression plasmid, mouse retinoid X receptor expression plasmid,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed