Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Wake Forest University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataKi:  1.72E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake in ASBT-expressing COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataIC50:  6.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human TGR5 Y89A mutant expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  680nMAssay Description:Agonist activity at wild type human TGR5 expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed