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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Ileal sodium/bile acid cotransporter
(Homo sapiens (Human))
Wake Forest University
Curated by
ChEMBL
Ligand
BDBM50375592
(CHEMBL412272)
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Affinity Data
Ki: 1.72E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of Taurocholate uptake in ASBT-expressing COS cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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ChEBI
CHEMBL
KEGG
PC cid
PC sid
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Article
PubMed
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
The Netherlands Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50375592
(CHEMBL412272)
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Affinity Data
IC50: 6.00E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
Heinrich Heine University
Curated by
ChEMBL
Ligand
BDBM50375592
(CHEMBL412272)
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Affinity Data
EC50: 8.90E+3nM
Assay Description:
Agonist activity at human TGR5 Y89A mutant expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
Heinrich Heine University
Curated by
ChEMBL
Ligand
BDBM50375592
(CHEMBL412272)
Copy SMILES
Copy InChI
Affinity Data
EC50: 680nM
Assay Description:
Agonist activity at wild type human TGR5 expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase re...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
G-protein coupled bile acid receptor 1
(Homo sapiens (Human))
Heinrich Heine University
Curated by
ChEMBL
Ligand
BDBM50375592
(CHEMBL412272)
Copy SMILES
Copy InChI
Affinity Data
EC50: 790nM
Assay Description:
Agonist activity at human TGR5 expressed in CHO cells by luciferase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI