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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Acadia Pharmaceuticals
US Patent
Ligand
BDBM193790
(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
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Affinity Data
EC50: 1.30nM
Assay Description:
NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Acadia Pharmaceuticals
US Patent
Ligand
BDBM193790
(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 79nM
T: 2°C
Assay Description:
Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
Acadia Pharmaceuticals
US Patent
Ligand
BDBM193790
(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
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Affinity Data
EC50: 500nM
Assay Description:
NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
Acadia Pharmaceuticals
US Patent
Ligand
BDBM193790
(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 40nM
Assay Description:
NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI