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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  240nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  240nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  430nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  430nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  650nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bcl-XL after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  750nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataIC50:  750nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Bcl-XL by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50316671((S)-1,(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Bcl-XL by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed