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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Medical University Of Lublin
Curated by
ChEMBL
Ligand
BDBM50348428
(CHEMBL1800961 | US9492405, 40)
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Affinity Data
Ki: 410nM
Assay Description:
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
Medical University Of Lublin
Curated by
ChEMBL
Ligand
BDBM50348428
(CHEMBL1800961 | US9492405, 40)
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Affinity Data
Ki: 1.66E+4nM
Assay Description:
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Medical University Of Lublin
Curated by
ChEMBL
Ligand
BDBM50348428
(CHEMBL1800961 | US9492405, 40)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.91nM
T: 2°C
Assay Description:
To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR, 1321N1 or U87MG cells were seeded in a 96-well plate at approximately 5,000 c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
Medical University Of Lublin
Curated by
ChEMBL
Ligand
BDBM50348428
(CHEMBL1800961 | US9492405, 40)
Copy SMILES
Copy InChI
Affinity Data
EC50: 133nM
Assay Description:
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Medical University Of Lublin
Curated by
ChEMBL
Ligand
BDBM50348428
(CHEMBL1800961 | US9492405, 40)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.400nM
Assay Description:
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI