Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataEC50:  60nMAssay Description:Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(RAT)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataEC50:  5.90nMAssay Description:Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataEC50:  4.90nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed