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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Angiotensin-converting enzyme
(Rattus norvegicus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50050151
(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
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Affinity Data
IC50: 0.300nM
Assay Description:
Inhibitory activity against angiotensin I converting enzyme
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Oryctolagus cuniculus (rabbit))
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50050151
(1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylamino)-...)
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Affinity Data
IC50: 3.80nM
Assay Description:
Inhibitory activity was tested against neutral endopeptidase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
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Affinity Data
IC50: 30nM
Assay Description:
In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibitory concentration against angiotensin I converting enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Tested in vitro for inhibition of neutral endopeptidase (NEP)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibitory concentration against neutral endopeptidase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
In vitro inhibition of purified rat kidney Neutral endopeptidase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048514
((S)-1-[(S)-2-((S)-2-Mercapto-3-phenyl-propionylami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI