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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
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Affinity Data
IC50: 0.130nM
Assay Description:
Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Glucocorticoid receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.130nM
Assay Description:
Transrepression of glucocorticoid receptor in PMA-stimulated human ChaGoK1 cells expressing TRE-LacZ construct assessed as inhibition of AP-1 mediate...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
Assay Description:
Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
Assay Description:
Binding affinity to GR (unknown origin) by FP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
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Affinity Data
IC50: 910nM
Assay Description:
Binding affinity to PR (unknown origin) by FP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Binding affinity to AR (unknown origin) by FP assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Estrogen receptor beta
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to ERbeta (unknown origin) by FP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Estrogen receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Binding affinity to ERalpha (unknown origin) by FP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50203419
(CHEMBL3915997)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of 3H-aldosterone from MR (unknown origin) ligand binding domain by SPA assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI