Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50062938(CHEMBL3397909 | N-[(3S)-1-Acryloyl-3-pyrrolidinyl]...)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of human ITKMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTyrosine-protein kinase ITK/TSK [357-620,Y512E](Homo sapiens (Human))
Glaxosmithkline

LigandBDBM50062938(CHEMBL3397909 | N-[(3S)-1-Acryloyl-3-pyrrolidinyl]...)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:This assay is based on the binding and displacement of Alexa-fluor 647-labeled ATP-competitive kinase inhibitor tracer 236. Binding of the tracer is ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI