Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM317530(6-chloro-3-[(1S)-1-({1H-pyrazolo[3,4-d]pyrimidin-6...)
Affinity DataIC50:  550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [1-390,401-414,R132C](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM317530(6-chloro-3-[(1S)-1-({1H-pyrazolo[3,4-d]pyrimidin-6...)
Affinity DataIC50:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent