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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  0.340nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217950((1R,5S,9R)-(+)-5-(3-hydroxyphenyl)-9-methyl-2-phen...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  3.10nMAssay Description:Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217950((1R,5S,9R)-(+)-5-(3-hydroxyphenyl)-9-methyl-2-phen...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  13nMAssay Description:Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  15nMAssay Description:Binding activity against kOpioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50217950((1R,5S,9R)-(+)-5-(3-hydroxyphenyl)-9-methyl-2-phen...)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  270nMAssay Description:Displacement of [125I]IOXY from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50067447(3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...)
Affinity DataKi:  272nMAssay Description:Binding activity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed