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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Angiotensin-converting enzyme
(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048506
(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
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Affinity Data
IC50: 8nM
Assay Description:
In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048506
(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.20nM
Assay Description:
In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Rattus norvegicus (Rat))
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048506
(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
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Copy InChI
Affinity Data
IC50: 49nM
Assay Description:
In vitro inhibitory activity against purified rat kidney neutral endopeptidase (NEP) using a fluorometric assay with dansyl-Gly-Phe-Arg as the substr...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Rattus norvegicus (Rat))
The Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50048506
(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 49nM
Assay Description:
In vitro inhibition of purified rat kidney Neutral endopeptidase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI