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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048506(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048506(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Affinity DataIC50:  8.20nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048506(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibitory activity against purified rat kidney neutral endopeptidase (NEP) using a fluorometric assay with dansyl-Gly-Phe-Arg as the substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048506(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of purified rat kidney Neutral endopeptidase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed