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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315672
(((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...)
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Affinity Data
Ki: 52nM
Assay Description:
Displacement of [3H] melanocortin-2 from human recombinant MC4 receptor expressed in CHO cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315672
(((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...)
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Affinity Data
EC50: 1.85E+3nM
Assay Description:
Agonist activity at human recombinant MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by enzyme fragment complementation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315672
(((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...)
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Affinity Data
EC50: 3.66E+3nM
Assay Description:
Agonist activity at human recombinant MC3 receptor expressed in CHO cells assessed as cAMP accumulation by enzyme fragment complementation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315672
(((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)...)
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Copy InChI
Affinity Data
EC50: 7nM
Assay Description:
Agonist activity at human recombinant MC4 receptor expressed in CHO cells by cAMP responsive beta lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI