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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
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Affinity Data
IC50: 0.780nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
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Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
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Copy InChI
Affinity Data
IC50: 54nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
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Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 280nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50340458
(CHEMBL1762009 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Agonist activity at human MC5 receptor expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI