Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
Ki: 11nMAssay Description:Antagonist activity assessed as inhibition of U50488-stimulated [35S]GTP-gamma-S binding to human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
IC50: 1.5nMAssay Description:Antagonist activity assessed as inhibition of loperamide-stimulated [35S]GTPgammaS binding to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
IC50: 2.30nMAssay Description:Antagonist activity assessed as inhibition of U50488-stimulated [35S]GTP-gamma-S binding to human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
BDBM50199931(3-((3S,7R,8R,9alphaR)-7,8-dimethyl-3-phenyl-octahy...)
IC50: 110nMAssay Description:Antagonist activity assessed as inhibition of BW373U86-stimulated [35S]GTP-gamma-S binding to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair