Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199908(3-((7R,8R,9alphaR)-7,8-dimethyl-2-(pyridin-4-ylmet...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199908(3-((7R,8R,9alphaR)-7,8-dimethyl-2-(pyridin-4-ylmet...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199908(3-((7R,8R,9alphaR)-7,8-dimethyl-2-(pyridin-4-ylmet...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity assessed as inhibition of loperamide-stimulated [35S]GTPgammaS binding to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed