Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50191347(CHEMBL3907376)
Affinity DataKi:  20nMAssay Description:Inhibition of full-length human TF/recombinant human factor 7a assessed as decrease in conversion of factor 10 to factor 10a by measuring S2765 hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50191347(CHEMBL3907376)
Affinity DataKi:  21nMAssay Description:Inhibition of human HK1 using H-D-Val-Leu-Arg-AFC as substrate assessed as release of AFC after 10 to 120 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50191347(CHEMBL3907376)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human factor 11a using pyroGlu-Pro-Arg-pNA as substrate assessed as release of pNA after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50191347(CHEMBL3907376)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human factor 10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA as substrate assessed as release of pNA after 10 to 120 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50191347(CHEMBL3907376)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using pyroGlu-Pro-Arg-pNA as substrate assessed as release of pNA after 10 to 120 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed