Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 33 hits in this display
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
Ki: 14.1nMAssay Description:uman or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according t...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
Ki: 31.6nMAssay Description:uman or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according t...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
Ki: 31.6nMAssay Description:uman or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according t...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
Ki: 39.8nMAssay Description:uman or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according t...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
Ki: 39.8nMAssay Description:uman or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according t...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 15nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 15nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 48.8nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 55.7nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 88.3nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 116nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 116nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 116nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 116nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 116nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: 171nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)
IC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
BDBM254164(US10112937, Example 44 | US10150765, Example 44 | ...)