Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 28 hits in this display
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
Ki: 25nMAssay Description:Displacement of [3H]-SB222200 from recombinant human NK3R expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
Ki: 29nMAssay Description:NK3: The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vit...More data for this Ligand-Target Pair
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
Ki: 29nMAssay Description:NK3: The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vit...More data for this Ligand-Target Pair
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
IC50: 33nMAssay Description:The antagonist activity of compounds of the invention is measured following pre-incubation (3 minutes) of the compound with the cells, followed by ad...More data for this Ligand-Target Pair
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
BDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)