Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  13nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50:  13nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: <50nMAssay Description:The purpose of this test is to test the in vitro inhibitory activities of the compounds against LSD1. The enzyme used in this experiment was human LS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-Glo.TM. Assay Kit according to the manufacturer's suggested protocol. Bri...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM151611(SP-2509 | US11433053, Example HCI-2509 | US8987335...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of monoamine oxidase activity was carried used using the MAO-GIo Assay Kit according to the manufacturer's suggested protocol. Briefly...More data for this Ligand-Target Pair
In DepthDetails US Patent