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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
44
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Target
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...)
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
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Affinity Data
IC50: 11.4nM
Assay Description:
Inhibition of Torpedo california AChE by Ellman's method
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of human AChE by Ellman's method
More data for this Ligand-Target Pair
Target Info
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KEGG
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3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
DrugBank
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GoogleScholar
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of AChE (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibitory concentration against human erythrocyte Acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 53nM
Assay Description:
Inhibition of bovine acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 53nM
Assay Description:
In vitro inhibitory concentration against rat cortex acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
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Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 65nM
Assay Description:
Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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B.MOAD
GoogleScholar
Ligand Info
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3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 72.4nM
pH: 5.0
Assay Description:
Inhibition of AChE in rat cortex at pH 5
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
In vitro inhibitory concentration against bovine acetylcholinesterase enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of acetylcholinesterase (AChE)activity in bovine erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
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MMDB
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PDB
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of bovine erythrocyte AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Inhibition of bovine AChE by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 82nM
Assay Description:
Inhibition of rat cortex homogenate acetylcholinesterase by spectrophotometric method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
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MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 82nM
Assay Description:
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 20 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 98nM
Assay Description:
Inhibition of AChE in rat cortex homogenate using acetylthiocholine iodide as substrate after 20 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Hoshi University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of bovine erythrocytes AChE using acetylthiocholine iodide as substrate incubated for 15 to 20 mins by Ellman's methods
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine chloride as substrate after 15 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
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CHEMBL
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In Depth
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PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 20 mins by by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
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In Depth
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
Inhibition of human erythrocyte AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
In vitro inhibitory concentration against acetylcholinesterase of human erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
Inhibition of acetylcholinesterase isolated from Human erythrocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured afte...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 600nM
Assay Description:
Inhibition of human acetylcholinesterase after 30 mins by microplate reader-based Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of AChE by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate after 5 mins by spectrophotometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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3D Structure (crystal)
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.17E+3nM
Assay Description:
Inhibition of Electric eel AChE using acetylcholine iodide as substrate by spectrophotometry based Ellman's method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.28E+3nM
Assay Description:
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by DTNB reagent based Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Reactome pathway
KEGG
UniProtKB/SwissProt
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3D Structure (crystal)
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Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human serum BChE
More data for this Ligand-Target Pair
Target Info
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KEGG
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Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibitory concentration against human plasma Butyrylcholinesterase
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Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
In vitro inhibitory concentration against BChE of human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of butyrylcholinesterase (BChE) in human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Sun Yat-Sen University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine chloride as a substrate incubated for 20 mins followed by substrate addition and measured aft...
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Carboxylic ester hydrolase
(Rattus norvegicus (rat))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: 3.64E+4nM
Assay Description:
Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate after 20 mins by by Ellman's method
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In Depth
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PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: 3.64E+4nM
Assay Description:
Inhibition of BuChE in rat serum using butyrylthiocholine iodide as substrate after 20 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
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PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: 5.62E+4nM
Assay Description:
In vitro inhibitory concentration against butyrylcholinesterase was determined using rat serum homogenate
More data for this Ligand-Target Pair
Target Info
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PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: 7.02E+4nM
Assay Description:
Inhibition of BuChE in rat serum
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Copy InChI
Affinity Data
IC50: 7.44E+4nM
Assay Description:
Inhibition of rat cortex homogenate BuChE by spectrophotometric method
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Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by Ellman's method
More data for this Ligand-Target Pair
Target Info
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KEGG
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of butyrylcholinesterase (BChE) activity in human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Canis lupus familiaris)
Hebei University
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
IC50: >1.00E+7nM
Assay Description:
Inhibition of dog serum BChE using butrylthiocholine iodide as substrate by spectrophotometry based Ellman's method
More data for this Ligand-Target Pair
Target Info
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+7nM
Assay Description:
Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate by DTNB reagent based Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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In Depth
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PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
The Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199522
((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
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Affinity Data
Kd: 17nM
Assay Description:
Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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In Depth
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PDB
3D Structure (crystal)
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