Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 36 hits in this display
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: 550nMAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: 550nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nM ΔG°: >-23.7kJ/molepH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
Ki: >1.00E+5nM ΔG°: >-23.7kJ/molepH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nM ΔG°: >-23.7kJ/molepH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
Ki: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
IC50: 56nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: 56nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: 56nMAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: 491nMpH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: 491nMAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: 491nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
IC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
IC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair
BDBM256458(US10329256, Example 2 | US9487512, 2 | US9944601, ...)
IC50: >1.00E+5nMAssay Description:Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s...More data for this Ligand-Target Pair