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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50172124
(2-[3-(Naphthalen-2-ylsulfanyl)-cyclohex-1-enylethy...)
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Affinity Data
Ki: 75nM
Assay Description:
Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor of rat cortical membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50172124
(2-[3-(Naphthalen-2-ylsulfanyl)-cyclohex-1-enylethy...)
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Affinity Data
IC50: 213nM
Assay Description:
In vitro inhibitory concentration against Ca+2 flux mediated by human mGlu5 receptor expressed in Ltk cells using fura-2 dye
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50172124
(2-[3-(Naphthalen-2-ylsulfanyl)-cyclohex-1-enylethy...)
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Affinity Data
IC50: 5.31E+3nM
Assay Description:
Inhibitory concentration against CYP1A2 using recombinant CYP450 under Gentest-based protocol
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI