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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Adenosine receptor A1
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM50186599
(8-cyclohexyl-2,6-diphenyl-9H-purine | CHEMBL207529...)
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Affinity Data
Ki: 0.730nM
Assay Description:
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM50186599
(8-cyclohexyl-2,6-diphenyl-9H-purine | CHEMBL207529...)
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Affinity Data
Ki: 118nM
Assay Description:
Displacement of [3H]ZM 241385 from human adenosine A2a receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A3
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM50186599
(8-cyclohexyl-2,6-diphenyl-9H-purine | CHEMBL207529...)
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Affinity Data
Ki: 200nM
Assay Description:
Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by
ChEMBL
Ligand
BDBM50186599
(8-cyclohexyl-2,6-diphenyl-9H-purine | CHEMBL207529...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 477nM
Assay Description:
Activity against human adenosine A1 receptor in CHO cells assessed by the antagonizing effect of 100 nM CPA on forskolin-induced cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI