Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL

LigandBDBM50036169(3-Selenophen-2-yl-1-aza-bicyclo[2.2.2]oct-2-ene | ...)Copy SMILESCopy InChI

Affinity DataKi:  410nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 by measuring displacement of [3H]-QNB from guinea pig cerebral cortexMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL

LigandBDBM50036169(3-Selenophen-2-yl-1-aza-bicyclo[2.2.2]oct-2-ene | ...)Copy SMILESCopy InChI

Affinity DataKi:  990nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M2 by measuring displacement of [3H]-QNB from guinea pig heartMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor(Cavia porcellus)
Uppsala University

Curated by ChEMBL

LigandBDBM50036169(3-Selenophen-2-yl-1-aza-bicyclo[2.2.2]oct-2-ene | ...)Copy SMILESCopy InChI

Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M3 by measuring displacement of [3H]-QNB from guinea pig parotid glandMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI